iCRT 14
CAS No. 677331-12-3
iCRT 14 ( iCRT14; iCRT-14; iCRT 14; Wnt inhibitor )
产品货号. M18982 CAS No. 677331-12-3
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥543 | 有现货 |
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10MG | ¥948 | 有现货 |
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25MG | ¥1588 | 有现货 |
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50MG | ¥2341 | 有现货 |
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100MG | ¥3475 | 有现货 |
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200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称iCRT 14
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
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产品描述iCRT14 is a potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40.3 nM). It inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of β-catenin/Tcf4 binding (Ki = 53.51 μM).
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同义词iCRT14; iCRT-14; iCRT 14; Wnt inhibitor
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通路Others
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靶点Other Targets
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受体Wnt
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研究领域Cancer
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适应症——
化学信息
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CAS Number677331-12-3
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分子量375.44
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分子式C21H17N3O2S
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纯度98%
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溶解度DMSO : ≥ 29 mg/mL; 77.24 mM
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SMILESO=C4S\C(=C/c2cc(C)n(c1cccnc1)c2C)C(=O)N4c3ccccc3
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化学全称5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Gonsalves FC, et al. Proc Natl Acad Sci USA. 2011 Apr 12;108(15):5954-63.
产品手册
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